Cellink BIO X Bedienungsanleitung
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BIO X
User manual
CELLINK AB
Arvid Wallgrens Backe 20
Gothenburg, SE 41346
SWEDEN
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Welcome to the world of bioprinng!
Not too long ago, the idea of creang living human ssue was no
more than a dream. Not anymore. The technology in front of you
is the next step on the path of regenerave medicine.
BIO X is designed with your research in mind. By simplifying
the 3D bioprinng process, you can focus on your research and
dream bigger than ever before.
Featuring unrivalled usability and versality, BIO X will help take
your research to the next level. With interchangeable intelligent
printheads, Clean Chamber technology, print chamber sterilizaon,
temperature-controlled print bed and a user-friendly interface,
BIO X is ready for the most complex 3D bioprinng challenges.
This manual will serve as your guide to geng started with BIO
X. Review the enre manual before using the product for the rst
me.
Welcome to the future of regenerave medicine!
Last update: 2019-03-12
Revision number 1.0
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Contents
1. Safety informaon...................................................................................................................................4
1.1 General safety informaon...................................................................................................6
1.2 Unpacking, liing and carrying.............................................................................................7
1.3 Electrical informaon.............................................................................................................7
1.4 Protecve equipment ...........................................................................................................7
1.5 Hazardous materials...............................................................................................................8
1.6 Compliance..............................................................................................................................8
1.7 Electrostac discharge protecon......................................................................................9
2. Specicaons..........................................................................................................................................10
2.1 Product map...........................................................................................................................12
2.2 Technical specicaons........................................................................................................14
3. Geng started........................................................................................................................................16
3.1 Unpacking BIO X....................................................................................................................18
3.2 Contents ..................................................................................................................................19
3.3 Seng up BIO X.....................................................................................................................20
3.4 Starng BIO X for the rst me..........................................................................................21
4. Bioprinng with BIO X..........................................................................................................................22
4.1 Clean Chamber.......................................................................................................................24
4.2 Bioprinng from a 3D model...............................................................................................25
4.3 Bioprinng droplets...............................................................................................................38
4.4 Ulies......................................................................................................................................43
5. Maintenance............................................................................................................................................50
5.1 Changing the HEPA lter.....................................................................................................52
5.2 Manual cleaning or sterilizaon..........................................................................................52
6. Terms and condions.............................................................................................................................54
6.1 General terms and condions.............................................................................................56
6.2 End User Licence Agreement (EULA).................................................................................61
6.3 Warranty...................................................................................................................................68
7. Printhead manuals...................................................................................................................................70
7.1 CELLINK pneumac-based printhead................................................................................72
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1. Safety informaon
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1. Safety informaon
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Review the enre manual, as well as the manuals for any accessories, before you start using BIO X.
Mishandling can lead to equipment damage and serious injury. The following symbols are used to
indicate risk of equipment damage or personal injury:
CELLINK AB
Arvid Wallgrens Backe 20
Gothenburg, SE 41346
Sweden
1.1 General safety informaon
If BIO X acts in a way that is not described by this manual, turn it o and contact CELLINK.
Use BIO X for its intended purposes only. Do not modify its instruments, subcomponents or
accessories. Do not open BIO X, disassemble BIO X or aempt any service other than the instrucons
described in the manual.
This symbol indicates presence of UV light. Keep the BIO X door closed and wear
proper safety are during UV sterilizaon and UV curing. This symbol appears on the
touchscreen when a UV light source is acve.
Never place your ngers near the machine unl all parts have stopped moving. Moving
parts can cause injury.
This symbol indicates risk of injury or equipment damage.
Never clean or service BIO X while the machine is on. Always turn o the power and
disconnect any external sources of power and air pressure before cleaning or servicing
BIO X.
This symbol indicates a heated surface. BIO X has heated surfaces that may cause
personal injury or equipment damage if not treated with care. A physical symbol labels
these surfaces on the BIO X, and the symbol appears on the BIO X touchscreen when
the print chamber is heated.
Manufacturer
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BIO X uses UV light for sterilizaon and curing. Never look directly at UV light. Never
expose skin to UV light. Eye or skin exposure can result in serious personal injury.
BIO X has heated surfaces that can reach temperatures up to 250 degrees Celsius.
Never touch heated surfaces when using the heang funcon. Always let printheads
and print bed cool aer using the heang funcon.
Always ensure that equipment is correctly mounted before use. Improperly mounted
print beds, printheads, cartridges, cables, liquid spouts and air spouts can be dangerous. If
any equipment appears damaged, turn o the machine, unplug all external connecons
and contact CELLINK before further use.
1.2 Unpacking, liing and carrying
BIO X is heavy. Always use a minimum of two people to unpack and move the machine.
Read how to safely unpack and setup BIO X in Chapter 3.
1.4 Protecve equipment
1.3 Electrical informaon
Always wear gloves and eye protecon during bioprinng, UV curing and sterilizaon.
Always wear gloves and eye protecon while handling hazardous materials, including
materials that are toxic, corrosive and carcinogenic.
Read the material safety data sheets, packing labels and the manufacturer or distributor’s
catalog before using the BIO X.
Always connect BIO X to a grounded socket and use the voltage described in the
specicaons. Improper electrical handling can cause equipment damage and personal
injury.
Never tamper with any safety interlocks. Tampering risks equipment damage and
personal injury.
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1.5 Hazardous materials
1.6 Compliance
Consult material safety data sheets, packaging labels and the manufacturer or distributor
catalog before handling hazardous dispensing materials, such as ammable and
corrosive materials. Ensure any operators are informed of the material’s characteriscs
and compability with the dispensing unit. Always use appropriate safety equipment
and are. If you are unsure of a material’s compability, contact CELLINK.
Aer using ethanol to clean BIO X, wait at least 60 seconds before bioprinng to
ensure that all ammable vapors are removed.
By using BIO X, you agree to the terms stated here and in the warranty (Chapter 6.) Except for
the express warranty set forth in the warranty informaon and in our soware license terms as
applicable, all equipment and soware provided hereunder are provided “as is,” and CELLINK makes
no warranty as to its use or performance. Except for any warranty, condion, representaon or term
the extent to which cannot be excluded or limited by applicable law, CELLINK and its suppliers make
no warranty, condion, representaon, or term (express or implied, whether by statute, common
law, custom, usage or otherwise) as to any maer including, without limitaon, noninfringement
of third party rights, merchantability, integraon, or tness for a parcular purpose. You assume
responsibility for selecng the soluon to achieve your intended results, and for the installaon
of, use of, and results obtained from the equipment and soware. Without liming the foregoing
provisions, CELLINK makes no warranty that the equipment or soware will be error-free or free from
interrupons or other failures or that the soware or equipment will meet your requirements. Under
no circumstances and under no legal theory, whether in tort, contract, or otherwise, shall CELLINK
or its suppliers be liable to purchaser or to any other person for loss of prots, loss of goodwill, or
any indirect, special, incidental, or consequenal damages, or damages for gross negligence of any
character. Under no circumstances can CELLINK be responsible for consequences of misuse of
the instrument or for use of the instrument outside the use specied in this user manual, be they
material or personal.
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1.7 Electrostac discharge (ESD) protecon protecon
1.7.1 Introducon
The BIO X print chamber is ESD-sensive. Use the following procedures to ensure that no damage
is caused to the BIO X or its accessories.
1.7.2 Procedures
Review the procedures to follow when using the BIO X print chamber and handling printheads.
Always discharge yourself before touching any ESD-sensive parts.
1.7.2.1 Discharging yourself
To discharge yourself, touch a grounded metal surface. Discharge yourself before touching printheads
or installing them in the BIO X. Examples of grounded metal surfaces include:
• Any metal surface in a laminar ow hood.
• Any metal sink.
• The frame of the BIO X when connected to a grounded power outlet, as well as any exposed
screws, including the screws on the le-side door hinges.
1.7.2.2 Using proper clothing
Avoid charging yourself to ensure ESD protecon. Wear clothes made out of coon when appropriate.
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2. Specicaons
Andere Handbücher für BIO X
3
Inhaltsverzeichnis
Andere Cellink 3D-Drucker Handbücher
