Illumina DRAGEN v3 Bedienungsanleitung

Illumina DRAGEN Server v3

Site Prep and Installation Guide

Introduction 1

Delivery and Setup 1

Facility Requirements 2

Electrical Requirements 2

Environmental Considerations 3

Network Considerations 4

Security and Safety 5

Set Up the DRAGEN Server 6

Configure BMC 10

Configure the Server Network 11

Set Server Time 12

Configure External Storage 13

Activate DRAGEN Software License 14

Install the DRAGEN Software 16

Access the Server Remotely 16

Shut Down the Server 17

Advanced Exchange 17

Server Specifications 20

Document # 1000000097923 v02

September 2020

ILLUMINA PROPRIETARY

For Research Use Only. Not for use in diagnostic procedures.

Revision History 21

Technical Assistance 22

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

This document and its contents are proprietary to Illumina, Inc. and its affiliates ("Illumina"), and are intended solely for

the contractual use of its customer in connection with the use of the product(s) described herein and for no other

purpose. This document and its contents shall not be used or distributed for any other purpose and/or otherwise

communicated, disclosed, or reproduced in any way whatsoever without the prior written consent of Illumina. Illumina

does not convey any license under its patent, trademark, copyright, or common-law rights nor similar rights of any third

parties by this document.

The instructions in this document must be strictly and explicitly followed by qualified and properly trained personnel in

order to ensure the proper and safe use of the product(s) described herein. All of the contents of this document must be

fully read and understood prior to using such product(s).

FAILURE TO COMPLETELY READ AND EXPLICITLY FOLLOW ALL OF THE INSTRUCTIONS CONTAINED HEREIN MAY

RESULT IN DAMAGE TO THE PRODUCT(S), INJURY TO PERSONS, INCLUDING TO USERS OR OTHERS, AND DAMAGE

TO OTHER PROPERTY, AND WILL VOID ANY WARRANTY APPLICABLE TO THE PRODUCT(S).

ILLUMINA DOES NOT ASSUME ANY LIABILITY ARISING OUT OF THE IMPROPER USE OF THE PRODUCT(S)

DESCRIBED HEREIN (INCLUDING PARTS THEREOF OR SOFTWARE).

All trademarks are the property of Illumina, Inc. or their respective owners. For specific trademark information, see

www.illumina.com/company/legal.html.

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

Introduction

This guide provides instructions for setting up the Illumina® DRAGEN™ Server, including preparing your site

for installation and operation. You can use the following specifications and guidelines included to prepare your

facility:

uSpace requirements

uElectrical requirements

uEnvironmental considerations

uComputing requirements

uNetwork considerations

Safety Considerations

See the

DRAGEN Bio-IT Platform Safety and Compliance Guide (document # 1000000096716)

for important

information about safety considerations.

Additional Resources

The DRAGEN Bio-IT Platform support pages on the Illumina website provide additional system resources.

These resources include software, training, compatible products, and the following documentation. Always

check support pages for the latest versions.

Resource Description

DRAGEN Bio-IT Platform Safety and

Compliance Guide (document #

1000000096716)

Provides information about operational safety considerations, compliance

statements, and labeling.

llumina DRAGENBio-ITPlatform User Guide

(document # 1000000070494)

Provides an overview of the platform and associated procedures. Instructions

for use, maintenance, and troubleshooting procedures are included.

Delivery and Setup

The DRAGEN Server v3 is unpacked and installed by the customer. The space must be ready before

delivery.

Box Dimensions

Use the following dimensions to determine transport, setup, and storage plans.

Measurement Dimension

Height 41.0 cm (16.0 in)

Width 85.1 cm (33.5 in)

Depth 62.2 cm (24.5 in)

Weight 33.1 kg (73 lb)

Shipping Box Components

The DRAGEN Server v3 and components are shipped in one box. The following components are included:

uPower cord, country-specific

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

uDRAGEN License USBkey

uRack mount rails

uRack mount screws

Facility Requirements

Use the specifications and requirements provided in this section to set up your lab space.

Equipment Dimensions

Measurement Dimension

Height 8.8 cm (3.5 in)

Width 47.8 cm (19 in)

Depth 49.32 cm (19.4 in)

Weight 16.10 kg (35 lbs)

Placement Requirements

Position the DRAGEN Server v3 to allow proper ventilation, access to one power outlet, and access for

servicing.

uAllow a rack height of at least 2U.

uMake sure that there is one standard pocket outlet within 10 ft (3 m) of the server.

uPosition the instrument so personnel can quickly disconnect the power cords from the outlets.

Electrical Requirements

Power Specifications

Power Specification

Power Supply Rating 1574 Watts at 100%. Maximum power draw under load

800 W

Input Voltage 100–240 V AC at 50/60 Hz, autoranging

Receptacles

Your facility must be wired with the following receptacles:

uFor 100–110 Volts AC—Two 10 amp grounded, dedicated lines with proper voltage and electrical

ground.

uFor 220–240 Volts AC—Two 6 amp grounded lines with proper voltage and electrical ground.

uNorth America and Japan—NEMA 5-15.

uIf the voltage fluctuates more than 10%, power line regulators are required.

Protective Earth

The has a connection to protective earth through the enclosure. The safety ground on the

power cord returns protective earth to a safe reference. The protective earth connection on

the power cord must be in good working condition when using this device.

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

Power Cords

The DRAGEN Server v3 has international standard IEC 60320 C13 receptacles and is shipped with one

region/country-specific power cords.

Hazardous voltages are removed from the DRAGEN Server v3 only when the power cords are disconnected

from the AC power source.

To obtain equivalent receptacles or power cords that comply with local standards, consult a third-party

supplier such as Interpower Corporation (www.interpower.com).

CAUTION

Never use an extension cord to connect the DRAGEN Server v3 to a power supply.

Fuses

The DRAGEN Server v3 contains no user-replaceable fuses.

Environmental Considerations

The following table specifies temperature, humidity, and other environmental considerations for safely housing

the instrument.

Element Specification

Temperature Maintain a server room temperature of 0°C to 40°C. This temperature is the operating

temperature of the DRAGEN Server v3. Do not allow the ambient temperature to vary by

more than ±2°C.

Humidity Maintain a noncondensing relative humidity between 10–95%.

Altitude Locate the DRAGEN Server v3 at an altitude below 2,000 meters (6,500 ft).

Air Quality Operate the server in a data center environment with air filtration per ISO 14644-1 Class 8

with a 95% upper confidence limit.

Ventilation Consult your facilities department for ventilation requirements sufficient for the level of heat

output expected from the DRAGEN Server v3.

Location Operate the server in an indoor environment only. The server is not suitable for use in

locations where children are likely to be present.

Heat Output

Measured Power Thermal Output

1100 Watts 4100 BTU/hr

Noise Output

A measurement of ≤ 70 dB is within the level of a normal conversation at a distance of approximately 1 meter

(3.3 feet).

Acoustical Performance Noise Output (dB)

Idle at 25°C Ambient 36

Max. Loading at 35°C Ambient <75

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

Uninterruptible Power Supply

Illumina recommends using a user-supplied uninterruptible power supply (UPS).

Illumina is not responsible for data loss caused by interrupted power, regardless of whether the DRAGEN

Server v3 is connected to a UPS. Standard generator-backed power is often not uninterruptible, so a brief

power outage occurs before power resumes. This power outage interrupts analysis and data transfer.

The following table shows three example recommended UPS models for the DRAGEN Server v3.

Specification Japan

APC Model

# SMX1500RMJ2U

North America

APC Model

# SMX1500RM2UNC

International

APC Model

# SMX1500RMI2UNC

Maximum

Output

Capacity

1200 W 1500 VA 1200 W 1440 VA 1200 W 1500 VA

Input Voltage

(Nominal)

100 VAC 120 VAC 230 VAC

Input

Frequency

50/60 Hz 50/60 Hz 50/60 Hz

Input

Connection

NEMA 5–15P NEMA 5–15P IEC-320 C14

Schuko CEE7/EU1-16P

British BS1363A

Built-In UPS

Output

Receptacles

Six NEMA 5–-15 R (battery backup) Eight NEMA 5–15R (battery

backup)

Eight IEC 320 C13 (battery

backup)

Dimensions 8.9 cm × 43.2 cm × 46.8 cm 8.9 cm × 43.1 cm × 49.0 cm

(3.5 in × 17.0 in × 19.3 in)

8.9 cm × 43.2 cm × 49.0 cm

Weight 27.8 kg 24.8 kg (54.6 lb) 24.8 kg

Typical Run

Time (at 500

Watt Average

Draw)

19.5 minutes 22.9 minutes 22.9 minutes

Table 1 Region-Specific UPS Recommendations

Network Considerations

Before running tests, make sure that your network contains the required components and meets the network

connection recommendations.

DRAGEN Server v3 setup requires the following network components:

uDefault gateway address

uDNS Server IP address

uIP addresses (2)

uSubnet mask for the IP addresses

The following operations require an external internet connection using TCP on ports 80 and 443:

uUpdating the software

uRemote assistance from Illumina Technical Support

uAccess to license server

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

Network Connections

Use the following recommendations to install and configure a network connection:

uRecommended bandwidth for a connection is as follows.

u10 Gb per second connection to storage.

uSwitches and other network equipment must have a minimum of 10 Gb per second.

uCalculate the total capacity of the workload on each network switch. The number of connected

instruments and ancillary equipment, such as a printer, can impact capacity.

uFor 10 Gb connections, SFP+ and RJ45 connections are supported. If using SFP+ ports, twinax cables

or SFP+ transceivers are required. Validated transceivers include Intel and Finisar.

uAsk your IT professional to review network maintenance activities for potential compatibility risks with the

system.

Third-Party Software

DRAGEN Server v3 does not support software beyond what is provided at installation. Do not install any

software that was not provided with the DRAGEN Bio-IT Platform. Third-party software is untested and can

interfere with performance and security.

User Behavior

The DRAGEN Server v3 is designed to analyze sequencing data. Do not consider it a general-purpose

computer. For quality and security reasons, do not use the computer for web browsing, checking email,

reviewing documents, or other unnecessary activity. These activities can result in degraded performance or

loss of data.

Security and Safety

The DRAGEN Server v3 is designed to resist attacks. Supplement this design with the following security

recommendations:

uA secure internal LAN to prevent the distribution of data to all web browsers.

uLimited access to the DRAGEN Server v3 to prevent the removal of the RAID controller, disk drives, and

access to data. Booting in single-user mode allows access to the whole system.

Antivirus Software

Illumina does not recommend running any virus scanners on the DRAGEN Server v3. Virus scanners often

impact the performance of High-Performance Computing (HPC) systems.

Restricted Ports and Authentication

Outbound Connections lus.edicogenome.com port 80

Inbound Connections SSH: TCP port 22

Stack Overflow Protection

Modern processors disable coded execution in data sections of the program to address stack overflow

attacks. By default, this feature is enabled.

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

Set Up the DRAGEN Server

This section provides information on installing the DRAGEN Server v3. Before beginning, make sure that you

have all the components and your facility meets the necessary requirements. For more information, see

Shipping Box Components

on page 1 and

Facility Requirements

on page 2.

The following components are not included with the DRAGEN Server v3 and required to set up the sever:

uMonitor with a HDMI input

uHDMI cable

uKeyboard with a USB input

uMouse with a USB input

uTwo USB cables

Install the Server Racks

Use the following instructions to mount the DRAGEN Server v3 to your server rack.

1 Pull the mounting bracket rail out from the rail assembly until you reach the safety lock.

2 Press the safety lock trigger down, and then remove the mounting bracket rail from the rail assembly.

3 Release the sliding lock on both ends of the rail assembly.

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

4 Extend the slide rail out from the rail assembly.

5 Insert the rail assembly end that was not extended into the server rack brackets.

An audible click indicates that the rail assembly is in place.

6 Push the rail assembly forward to secure.

7 Insert the other end of the rail assembly into the server rack brackets.

An audible click indicates that the rail assembly is in place.

8 Push the sliding locks forward to secure.

Document # 1000000097923 v02

For Research Use Only. Not for use in diagnostic procedures.

Illumina DRAGEN Server v3 Site Prep and Installation Guide

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