Agilent Technologies 3200 Series Bedienungsanleitung

3200 Series Meters

Installation Qualification

Operation Qualification

Performance Verification

Reference Document

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 2 of 13

Table of Content

1. Introduction…………………………………………………….3

1.1 General Information…………………………………………………….3

1.2 Meter Information……………………………………………………….3

1.3 Required Materials…………………………………………………….. 3

1.4 Meter Keys……………………………………………………………….5

1.5 Meter connections………………………………………………………5

2. Installation Qualification…………………………………….5

2.1 Overview………………………………………………………………….5

2.2 Meter Information……………………………………………………….6

2.3 Environment Condition………………………………………………..6

2.4 Document Inspect………………………………………………………6

2.5 Component Check……………………………………………………...6

2.6 Reference Standard Information……………………………………..6

3. Operation Qualification……………………………………...6

3.1 Meter Power Supply……………………………………………………7

3.2 Meter Self-Test………………………………………………………….7

3.3 Manual Temperature Verification…………………………………….8

3.4 pH electrode Calibration……………………………………………….8

3.5 ISE electrode Calibration………………………………………………8

3.6 DO Probe Calibration…………………………………………………..8

3.7 Conductivity Probe Calibration………………………………………9

4. Performance Verification…………………………………10

5. Appendix Documents……………………………………….10

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 3 of 13

1. Introduction

1.1 General Information

This standard operating procedure (SOP) defines the procedure for the installation

qualification, operation qualification and performance verification (IQ/OQ/PV) of Agilent 3200

series meters. This procedure provides a guideline to generate the data necessary to validate

or qualify the Agilent 3200 series meters.

This SOP is applicable to all Agilent 3200 series meters that are used in a regulated lab. And

this SOP can be used as a reference for customer to develop their own IQ/OQ/PV documents.

It’s customers’responsibility to develop and maintain the IQ/OQ/PV SOP for their specific

applications.

1.2 Meter Information

Installation qualification and operation qualification are required for all new meters used in a

regulated environment. The meters will not be released for regulated use until the installation

qualification and operation qualification have been performed with passing result.

Part Number

Description

Measurement Function

G4383-64000

Agilent 3200P Benchtop pH Meter

pH,ORP

G4384-64000

Agilent 3200C Benchtop Conductivity Meter

Conductivity

G4385-64000

Agilent 3200D Benchtop Dissolved Oxygen Meter

Dissolved Oxygen

G4386-64000

Agilent 3200I Benchtop Ion Meter

ISE

G4387-64000

Agilent 3200M Benchtop Multi-Parameter Analyzer

pH, ORP, Conductivity,

Dissolved Oxygen, ISE

1.3 Required Material

The following materials are required to perform the IQ/OQ/PV onAgilent 3200 series meters

Short circuit plug, PN: G4383-40000, shipped with 3200P/3200M/3200I

Conductivity diagnostic tool, PN:5185-8391, shipped with 3200C/3200M

ATC temperature diagnostic tool, PN: 5185-8390, shipped with

3200P/3200M/3200I/3200C/3200D

Manuals/User Guide

For 3200P/3200M with pH function:

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 4 of 13

pH electrode or pH combination electrode or pH triode combination electrode, with

BNC connector

pH buffers

Option

Agilent Standard Solution

Part Number

Package

Shelf Life

pH4.001 buffer (NIST)

5190-0535

3 x 250ml

15 months

pH7.00 buffer (NIST)

5190-0537

3 x 250ml

15 months

pH10.01 buffer (NIST)

5190-0536

3 x 250ml

15 months

pH4.00 buffer (GB)

5190-0538

3 x 250ml

15 months

pH6.86 buffer (GB)

5190-0539

3 x 250ml

15 months

pH9.18 buffer (GB)

5190-0540

3 x 250ml

15 months

pH buffer package (4.01、7.00、

10.01) (NIST)

5190-0533

3 x 250mL

15 months

pH buffer package (4.00、6.86、

9.18) (GB)

5190-0533

3 x 250mL

15 months

Select one option from the list. Each option contains three standard buffers.

For 3200I/3200M with ISE function:

Ion selective electrode (ISE) with BNC connector

Certified ISE standards appropriate for ion selective electrode, for example, NaF for

fluorion measurement with I9111 Fluoride combination ISE. Agilent don’t supply ISE

standards.

For 3200C with conductivity function:

Conductivity probe with 3 pin mini DIN connector

Certified conductivity standards appropriate for conductivity probe. Agilent don’t

supply conductivity standards.

For 3200D with DO function:

Dissolved Oxygen probe with 4 pin miniDIN connector

Zero Oxygen solution for Zero Oxygen Calibration, freshly prepared by customers.

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 5 of 13

1.4 Meter Keys

1.5 Meter Connections

All connectors on 3200M are listed above. 3200P/3200I/3200D/3200C will have fewer

connectors. For example, 3200P with all these listed connectors except Conductivity 3 pin

MiniDIN connector.

1.6 Qualification Scope

1.6.1 Installation Qualification

Verify and document that a system is installed according to written and pre-approved

specification. Provide assurance that the system specified for a particular function was

received, installation procedures were followed and the system was installed according

to customer/manufacturer’s specifications.

1.6.2 Operation Qualification

Verify and document that a system operates according to written and pre-approved

specification throughout. Provide assurance that the system operates according to

BNC Connector

4 pin MiniDIN

Connector

3 pin MiniDIN

Connector

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 6 of 13

customer/manufacturer’s specifications.

1.6.3 Performance Verification

Verify and document the measurement accuracy and precision according to

specifications.

2. Installation Qualification

2.1 Overview

Before performing the IQ/OQ/PV, examine the meter for abnormal conditions such as

corrosion, deterioration, loose components, broken parts and environmental conditions.

Correct any of these conditions before installation.

Installation qualification of new meters includes verifying meter information, reviewing

pre-installation requirements and confirming environment conditions.

2.2. Meter Information

2.2.1 Record the start date.

2.2.2 Record the location of the meter.

2.2.3 Record the person responsible for the meter.

2.2.4 Describe the meter appearance.

2.2.5 Describe the application or purpose of the meter.

2.3 Environmental Conditions

Inspect the site prior to installation and verify that all the meter operating conditions are met.

Check the electrical/power supply. Inspect the equipment for abnormal conditions. Record

and correct all abnormal conditions.

2.4 Documentation Inspection

2.4.1 Obtain all manuals supplied with the meter.

2.4.2 Record the part number and title of theses manuals.

2.4.3 Check the certificate of the meter.

2.5Component Check

2.5.1 Give a detailed description of all meter components.

2.5.2 Record the information for all components including the component type, serial number

and firmware version.

2.6Reference Standards Information

2.6.1 Record the last calibration data and calibration due date

2.6.2 Check the Standards shelf life

3 Operational Qualification

Operation qualification of new meters demonstrates correct meter operation by verifying the

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 7 of 13

meter self-test and pH, ORP, ISE, DO and conductivity functionality.

For detailed calibration procedures refer to the User Guide of 3200 series meters.

3.1 Meter Power Supply

Check the power adapter input and output.

They should meet: Input 240 VAC, 1A

Output 9VDC, 800mA

3.2 Meter Self-Test

3.2.1 Temperature test for all meters

Connect the ATC temperature diagnostic tool (PN:5185-8390) to the Temp. socket of

meters;

Turn on the meter to enter into measurement state.

The meter should display a temperature reading between 49.0 to 51.0 °C.

3.2.2 Check the potential (mV) value for 3200P/3200I/3200M

Disconnect the pH electrode.

Connect the short circuit plug (PN:G4383-40000) to the pH socket.

Turn on the meter.

Start measuring pH.

The meter should display a potential (mV) reading between -0.5 to 0.5 mV (also

called mV Zero).

3.2.3 Check pH value for 3200P/3200M

Disconnect the ATC probe if plugged.

Set the temperature to 25 °C manually.

Connect the short circuit plug (PN:G4383-40000) to the pH socket.

When the potential (mV) is zero, the meter should display pH 7.00 (±0.01).

3.2.4 Check pX value for 3200I/3200M

Disconnect the ATC probe if plugged.

Set the temperature to 25 °C manually.

Connect the short circuit plug (PN:G4383-40000) to the pH socket.

When the potential (mV) is zero, the meter should display pX 2.00 (±0.01).

3.2.5 Check for current Response for 3200D/3200M

Connect the meter with the ATC temperature diagnostic tool (PN:5185-8390) shipped

with the meter.

Turn on the meter. Enter the measurement state.

The meter should display a current between 680 to 720 nA.

When the diagnostic tool is unplugged, the meter should display a current from 0 to 5

nA.

3.2.6 Check conductivity for 3200C/3200M

Disconnect the ATC temperature diagnostic tool if plugged and manually set the

temperature to 25°C.

Connect the meter with conductivity diagnostic tool (PN:5185-8391) shipped with the

meter.

Turn on the meter. Enter the measurement state.

It will display:

Conductivity: nearly 100 μS/cm

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 8 of 13

Resistance: nearly 10 kΩ·m

3.3 Manual Temperature Verification

Disconnect all of the electrodes and probes from the meter.

In the measurement mode, the temperature display should be 25.0±0.1°C

3.4 pH Electrode Calibration (Meters with pH function)

The calibration points should cover the expected pH range of the samples to be measured.

The calibration points should be not less than 1 pH unit apart and not more than 4 pH units

apart. Fresh buffers should be used for each calibration.

Prepare the electrode and ATC probe (if necessary). Connect the electrode and ATC

probe to the meter.

Select appropriate standard solution and press [Calibration] key from the meter

interface.

Clean pH electrode, reference electrode (if separated) and ATC probe (if separated).

Put them in the buffer to be calibrated.

When the reading becomes stable, press [Enter] key and the meter will display

‘Storing……’ and save calibration data.

Repeat until all buffers are calibrated.

After calibration, you could review the actual electrode slope, in percent. The slope

must be in the range of 90% to 102%.

3.5 ISE Electrode Calibration (Meters with ISE function)

The calibration standards should cover the expected concentration of the samples to be

measured and the calibration range should be at least ten times greater than the lowest

calibration point. Control the calibration solution and sample solution at the same temperature.

If not, the measuring accuracy and reproducibility will be affected. Calibrate ISE in these

solutions from low concentration to high concentration. Fresh standards should be used for

each calibration.

Prepare the ISE and ATC probe (if necessary). Connect the electrode and ATC probe

to the meter.

Select ion mode and press [Calibration] from the meter interface.

Clean ISE and ATC probe (if necessary). Put them in standard solutions to be

calibrated in order from low to high concentration.

When the reading becomes stable, press [Enter] key and the meter will display

‘Storing……’ and save calibration data.

Repeat until all buffers are calibrated.

After calibration, you could review the actual electrode slope, in percent. The slope

must be in the range of 90% to 102%.

3.6 DO Probe Calibration (Meters with Dissolved Oxygen function)

Prepare the DO probe and connect it to the meter.

You may select either ‘Zero Oxygen Calibration’ or ‘Full Scale Calibration’ from the

meter interface.

Full Scale Calibration:

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 9 of 13

Thoroughly rinse the DO probe with DI water; Dry it with a soft tissue on the

membrane surface. To calibrate with air, put the probe in a well-ventilated area.

OR calibrate with water saturated with air as below,

Swirl the probe at a speed of 20–80 cm/s or stir the water to produce a similar linear

speed. Keep the flow speed constant during calibration. Ensure there is no air bubble

trapped under the membrane.

From the initial state or while measuring, press [Calibrate]; Select Full Scale. Press

[Enter]; when reading becomes stable, press [Enter] to automatically record the Full

Scale response. This ends Full Scale Calibration.

Zero Oxygen Calibration

Prepare zero-oxygen water by dissolving 12.5 g AR grade anhydrous sodium sulfite in

250 mL DI water; Soak the measuring tip in zero oxygen water and gently shake the

probe to remove bubbles on the gas permeation membrane surface; From the initial

state or while measuring, press [Calibrate]; Select Calib Zero; Press [Enter] to

select Zero Point Calibration. When reading becomes stable, press [Enter] to

automatically record the Zero Point value. This ends Zero Oxygen Calibration.

3.7 Conductivity Probe Calibration (Meters with Conductivity function)

3.7.1 Prepare the conductivity probe and connect it to the meter.

3.7.2 Calibrate the cell constant

Prepare a standard solution (KCl) according to page 37 of 3200C User Guide.

Ensure the meter is connected with both a conductivity probe and an ATC probe.

Record the actual temperature of sample solution.

Disconnect the ATC probe. The meter will display 25.0 °C by default. Pay attention to:

If the temperature is set at 25.0 °C manually, conductivity displayed is without

temperature compensation.

Rinse the conductivity probe with distilled or DI water. Soak the conductivity probe in

the standard solution.

Press [Calibrate]. Select Cell Const.

Press [Setup] to enter a Standard Solution Value (STD Value).You could find the

proper STD value on page 39 of 3200C User Guide with the temperature recorded.

When the reading stabilizes, press [Enter]. The meter will calculate and set the new

cell constant. The calibration is done.

3.7.3 Calibrate the TDS

Select a proper standard solution according to the nature and conductivity range of

sample.

Set the cell constant to the value written on the probe label or recalibrate the probe to

get a new cell constant in 3.7.2.

Press [Calibrate] and select TDS Factor. Press [Enter] to enter Calibration mode.

Rinse the conductivity probe with DI water.

The temperature of the calibration solution should be 25.0 ± 0.1 °C.

Soak the conductivity probe in the standard solution.

Press [Setup].

Enter an STD value (mg/L) given in Table 6 on page 41 of 3200 C User Guide.

When the reading becomes stable, press [Enter].

Issued: 01-05-2012 Revision: 1.0 Copyright 2012 Agilent Technologies

Page 10 of 13

The meter automatically calculates and sets a new TDS factor. Calibration is done.

4. Performance Verification

For performance verification, evaluation of accuracy, inter-assay RSD and intra-assay RSD

will consist of at least three measurement sets. Each set will measure pH of three test

samples representing low, medium and high pH value. The test buffers were the same as the

standard buffers. To evaluate precision of the inter-assay and the intra-assay, three

measurement sets must be conducted in three different days. The acceptance criterion is

bracketed in the table in appendix document.

The accuracy and the precision of pH meter should be validated. Measure three testing

buffers. Each buffer is measured six times continuously. Repeat the procedure three times;

each repeat should be at least 24 hours apart. Calculate intra-day and inter-day RSD%.

5. Appendix

5.1 Change history

Date

Author

Reason For Change

5.2 IQ - Mete Information

Start Date

Responsible Person

Location

Model

Description

Application

5.3 IQ –Environmental Conditions

Environmental Conditions

Ambient

Temperature

0-40 °C

Relative Humidity

5-85%

Power Supply

Power Adaptor

Voltage

Power input: 100 to 240 VAC, 1 A

Power output: 9 VDC, 1 A

Frequency

50/60 Hz

5.4 IQ - Component Information

Available

Not

Available

Model

Firmware Version

Serial No.



Checked by

Date

Verified by

Date

Dieses Handbuch passt für folgende Modelle

Inhaltsverzeichnis

Andere Agilent Technologies Messgerät Handbücher

Agilent Technologies

Agilent Technologies 8614 B Series Bedienungsanleitung

Agilent Technologies

Agilent Technologies 89410A Bedienungsanleitung

Agilent Technologies

Agilent Technologies N5242A Bedienungsanleitung

Agilent Technologies

Agilent Technologies 4285A Bedienungsanleitung

Agilent Technologies

Agilent Technologies 16753A Bedienungsanleitung

Agilent Technologies

Agilent Technologies G6691A Bedienungsanleitung

Agilent Technologies

Agilent Technologies 16850 Series Bedienungsanleitung

Agilent Technologies

Agilent Technologies E4980A Bedienungsanleitung

Agilent Technologies

Agilent Technologies 1145A Handbuch

Agilent Technologies

Agilent Technologies E4406A VSA Series Handbuch

Agilent Technologies

Agilent Technologies 4339B Bedienungsanleitung

Agilent Technologies

Agilent Technologies E4418B Bedienungsanleitung

Agilent Technologies

Agilent Technologies 6890 Series Bedienungsanleitung

Agilent Technologies

Agilent Technologies 2100 Bioanalyzer System Betriebsanleitung

Agilent Technologies

Agilent Technologies 10400B Series Bedienungsanleitung

Agilent Technologies

Agilent Technologies E8362B Bedienungsanleitung

Agilent Technologies

Agilent Technologies 8753ET Bedienungsanleitung

Agilent Technologies

Agilent Technologies 4339B Bedienungsanleitung

Agilent Technologies

Agilent Technologies 83483A Bedienungsanleitung

Agilent Technologies

Agilent Technologies 85103E Bedienungsanleitung

Agilent Technologies

Agilent Technologies 85052A Betriebsanleitung

Agilent Technologies

Agilent Technologies PNA Series Bedienungsanleitung

Agilent Technologies

Agilent Technologies 8719D Bedienungsanleitung

Agilent Technologies

Agilent Technologies 8757D Installations- und Betriebshandbuch

Beliebte Messgerät Handbücher anderer Marken

Suaoki

Suaoki D40 Bedienungsanleitung

Elster

Elster BK-G1.6 Bedienungsanleitung

Endress+Hauser

Endress+Hauser Deltabar FMD71 Handbuch

Duratool

Duratool D03128 Bedienungsanleitung

Vega

Vega VEGAPULS 65 Bedienungsanleitung

Tonghui

Tonghui TH2618B Bedienungsanleitung

Tenmars

Tenmars TM-801 Bedienungsanleitung

MSR

MSR 145 Bedienungsanleitung

TPS

TPS WP-82 Bedienungsanleitung

ELMETRON

ELMETRON CP-511 Bedienungsanleitung

PCB Piezotronics

PCB Piezotronics 003C30 Bedienungsanleitung

Tenma

Tenma 72-10465 Bedienungsanleitung

Endress+Hauser

Endress+Hauser Proline Promag 50 Technische Daten

Siemens

Siemens SITRANS F Coriolis FCT030 Stücklistenhandbuch

KLINGER

KLINGER CMF V Series Bedienungsanleitung

EXFO

EXFO FTB-2 Bedienungs- und Wartungshandbuch

Keysight

Keysight M8290A Bedienungsanleitung

ADTEK

ADTEK MW-5 Bedienungsanleitung