Endress+Hauser Analytikjena Biometra TMS Bedienungsanleitung

Installation Instructions

Biometra TMS

Temperature Measuring System for Thermal

Cyclers

Manufacturer Analytik Jena GmbH+Co. KG

Konrad-Zuse-Straße 1

07745 Jena, Germany

Phone +4936417770

Fax +493641779279

Email: [email protected]

Technical Service Biometra GmbH

Rudolf-Wissell-Straße 15

37079 Göttingen / Germany

Phone: +49 3641 77 7407

Fax: +49 3641 77 9279

E-mail: [email protected]

General Information http://www.analytik-jena.com

Documentation Number 34-9000-000-23

Edition B (09/2022)

Technical Documentation Analytik Jena GmbH+Co. KG

For a proper and safe use of this product follow the instructions. Keep the

operating manual for future reference.

Biometra TMS Table of contents

Table of contents

1 Notes on this operating manual........................................................................................................................... 5

2 Intended use......................................................................................................................................................... 6

3 Security ................................................................................................................................................................. 7

3.1 Safety labeling on the device ........................................................................................................................... 7

3.2 Requirements for the operating personnel..................................................................................................... 7

3.3 Safety instructions, transport and commissioning ......................................................................................... 7

3.4 Safety instructions: during operation .............................................................................................................. 8

3.4.1 General safety instructions during operation.................................................................................................. 8

3.4.2 Safety instructions – protection against explosion and fire........................................................................... 8

3.4.3 Safety instructions: electrical equipment ........................................................................................................ 8

3.4.4 Handling of auxiliary and operating materials and samples ......................................................................... 8

3.4.5 Safety instructions – maintenance and repair ................................................................................................ 9

3.5 Behavior during emergencies .......................................................................................................................... 9

4 Installation and commissioning ........................................................................................................................... 10

4.1 Installation prerequisites.................................................................................................................................. 10

4.1.1 Spatial requirements ........................................................................................................................................ 10

4.1.2 Power supply..................................................................................................................................................... 10

4.2 Installation ........................................................................................................................................................ 11

Table of contents Biometra TMS

Biometra TMS Notes on this operating manual

1 Notes on this operating manual

Content The operating manual describes the following device model:

¡BiometraTMS

Within this document, this model will be referred to as the device or the temperature

measuring system.

The device is used to calibrate automated and manually operated thermal cyclers.

As part of the detailed operating manual, these installation instructions contain the first

steps for commissioning the device as well as the safety instructions. For all subsequent

steps, please refer to the detailed operating manual which you will find in electronic for-

mat on the USB flash drive delivered with the product.

The device is intended to be operated by qualified specialist personnel who must ob-

serve all instructions given in the detailed operating manual.

The device has a modular design. The multimeter has its own separate operating man-

ual.

Conventions Instructions for actions occurring in chronological order are numbered and combined

into action units.

Warnings are indicated by a warning triangle and a signal word. The type, source and

consequences of the hazard are stated together with notes on preventing the hazard.

Elements of the control and analysis program are indicated as follows:

¡Program terms are in bold (e.g., the System menu).

¡Menu items are separated by vertical lines (e.g., System|Device).

Symbols and signal words used

in this manual

The user manual uses the following symbols and signal words to indicate hazards or in-

structions. These warnings are always placed before an action.

WARNING

Indicates a potentially hazardous situation which can cause death or very serious (possi-

bly permanent) injury.

CAUTION

Indicates a potentially hazardous situation which can cause slight or minor injuries.

NOTICE

Provides information on potential material or environmental damage.

Intended use Biometra TMS

2 Intended use

The BiometraTMS is a temperature measuring system for calibrating thermal cy-

clers. The measured temperatures of the sample block under test are compared with

specific predefined values.

NOTICE!The temperature measuring system cannot be used for adjusting the de-

vice. The calibration can only be used to determine and document possible devia-

tions. Adjustment must be carried out separately.

If at the end of the calibration process the control software reports that the thermal

cycler has failed the test, you should contact the Service department to arrange the

temperature readjustment of the device.

Regular calibration of the sample block temperature ensures compliance with the

temperature specifications and thus reliable test results.

The temperature measuring system has a modular design. A simple plug-in connec-

tor system ensures easy replacement of the measuring tree and allows testing ther-

mal cyclers with sample blocks of different sizes. Suitable measuring trees for the

various sample blocks can be obtained via the company Analytik Jena.

The measuring trees that are available allow calibrating automated and manually

operated thermal cyclers.

BiometraTMS can also be used to calibrate the heated lid. This calibration process

can be carried out in addition to the sample block calibration.

The software provides a number of configuration and display options. The intuitive

and easy-to-use structure of the software provides a convenient way to navigate

through the individual steps of the calibration. Information boxes and tool tips make

it easier to understand the process.

The device and its components may only be used for the analyses listed in the user

manual. Only this specified use is regarded as the intended use, ensuring the safety

of the user and the device.

The device must only be operated by specialist personnel trained by Analytik Jena.

Biometra TMS Security

3 Security

For your own safety and to ensure error-free and safe operation of the device, please

read this chapter carefully before commissioning.

Observe all safety instructions listed in this user manual and all messages and infor-

mation displayed on the monitor by the control and analysis software.

3.1 Safety labeling on the device

Warning and mandatory action labels have been attached to the device and must al-

ways be observed.

Damaged or missing warning and mandatory action labels can cause incorrect ac-

tions leading to personal injury or material damage. The labels must not be removed.

Damaged warning and mandatory action labels must be replaced immediately!

Also refer to the information provided in the operating manual of the multimeter for

details on the warning and mandatory action labels.

3.2 Requirements for the operating personnel

The device must only be commissioned, operated and serviced by qualified specialist

personnel who have been instructed by Analytik Jena. This instruction also includes

imparting the contents of this user manual and the user manuals of the connected

system components.

In addition to the safety instructions in the operating manual, the general applicable

safety and accident prevention regulations of the respective country the device is op-

erated in must be observed and adhered to. The operator must verify that they are

referring to the latest version of these regulations.

The operating manual must be accessible to the operating and service personnel.

3.3 Safety instructions, transport and commissioning

To prevent health damage, the following must be observed when moving the device

in the laboratory (lifting and carrying):

¡The device has no carrying handles. To transport the device, grip the device

firmly at the bottom with both hands and lift it.

¡Switch off the device before transporting it.

¡Insufficiently secured components pose a risk of injury. During transport, secure

the device components as specified in this operating manual.

¡Loose parts must be removed from the system components and packed sepa-

rately.

¡Risk of damage to health due to improper decontamination! It is not possible to

disinfect the temperature measuring system itself. Only use the temperature

measuring system in thermal cyclers that have been cleaned, disinfected and

dried beforehand! Before returning the device to Analytik Jena, clean the device

with a damp cloth, allow it to dry and document the cleaning measures taken.

Security Biometra TMS

3.4 Safety instructions: during operation

3.4.1 General safety instructions during operation

The operator must make sure that the device and its safety equipment is in sound

condition each time before starting up the device. This applies in particular after

each modification or extension of the device or its repair.

Observe the following:

¡The device may only be operated if all items of protective equipment (e.g. covers

in front of electronic components) are in place, properly installed and fully oper-

ational.

¡The sound condition of the protection and safety equipment must be checked

regularly. Any defects must be corrected as soon as they occur.

¡Protective and safety equipment must never be removed, modified or switched

off during operation.

¡The ventilation equipment on the device must be in good working condition.

Covered ventilation grilles or slots etc. may cause the device to break down or

may cause damage to it.

¡Ensure that no liquid enters the interior of the device, for example at cable con-

nections. There is a danger of electric shock.

¡Keep all combustible materials away from the device.

3.4.2 Safety instructions – protection against explosion and fire

The device may not be operated in an explosive environment.

Smoking or handling open flames are prohibited in the room in which the device is

operated!

3.4.3 Safety instructions: electrical equipment

Lethal voltages may occur in the device! Contact with live components may cause

death, serious injury or painful electrical shock.

¡Please observe the information on the electronics provided in the multimeter's

operating manual!

¡The measuring tree must only be plugged in or unplugged from the multimeter

after the multimeter has been switched off using the power button at the front

of the device.

¡Before starting any maintenance and repair work the device must be switched

off using the power button on the front of the multimeter and the power plug

must be removed from the power outlet!

¡Work on the electronics and in the interior of the device may only be carried out

by the customer service of Analytik Jena and specially authorized technicians.

3.4.4 Handling of auxiliary and operating materials and samples

The operator is responsible for the selection of substances used in the process as well

as for their safe handling. This is particularly important for radioactive, infectious,

poisonous, corrosive, combustible, explosive and otherwise dangerous substances.

When handling hazardous substances, the locally applicable safety instructions and

instructions in the safety data sheets from the manufacturers of the auxiliary and op-

erating materials must be complied with.

Biometra TMS Security

¡Avoid biological contamination of the device. The housing of the measuring

head cannot be disinfected and can only be wiped with a damp cloth. Clean, dis-

infect and dry the thermal cycler to be tested, and especially the sample block,

before inserting the measuring head.

¡The operator is responsible for carrying out suitable decontamination should the

device itself be contaminated with dangerous substances.

¡Splashes, drops or larger liquid spillages should be removed using an absorbent

material such as absorbent cotton, laboratory wipes or cellulose.

¡The tubes on the measuring tree must not come into contact with substances

containing oil. The operator must ensure the absence of all substances contain-

ing oil on the surface of the block and in the wells of the thermal cycler that is

supposed to be measured.

3.4.5 Safety instructions – maintenance and repair

The device is generally maintained by the customer service department of Analytik

Jena or specialist personnel trained and authorized by them.

Unauthorized maintenance can damage the device. For this reason, only the activi-

ties described in the user manual in the "Maintenance and care" chapter may be per-

formed by the operator.

¡All maintenance and repair work on the device must only be carried out when

the device is switched off (unless specified otherwise).

¡Only clean the exterior of the device with a slightly moistened, non-dripping

cloth. Use only water and, if required, customary surfactants.

¡The only suitable cleaning method for the multimeter housing is cleaning by

wiping. If the cleaning agent used has a spray nozzle, spray some of the cleaning

agent onto a suitable piece of cloth before using it on the device.

¡Do not use organic solvents or abrasives to clean the device.

¡It is not possible to disinfect the temperature measuring system itself. Only use

the temperature measuring system in thermal cyclers that have been cleaned,

disinfected and dried beforehand!

¡All protective equipment must be reinstalled and checked for proper function

when the maintenance or repair work is complete.

¡Use only original spare parts, wear parts and consumables. These have been

tested and ensure safe operation.

3.5 Behavior during emergencies

If there is no immediate risk of injury, switch off the device and the connected system

components immediately in hazardous situations or in the event of an accident and/

or disconnect the power plugs from the power outlets.

Installation and commissioning Biometra TMS

4 Installation and commissioning

4.1 Installation prerequisites

Climatic conditions The requirements for the climatic conditions at the installation location are set out in

the specifications. If required, ensure that the room is temperature-controlled.

Installation location require-

ments

¡This laboratory device is designed for inside use.

¡Do not use the device in wet and damp environments. Keep the device surface clean

and dry.

¡Avoid direct sunlight and radiation from heaters onto the device. If necessary, pro-

vide air conditioning.

¡Do not locate the device near sources of electromagnetic interference.

¡Avoid mechanical shocks and vibrations.

¡Do not use the device in explosion-hazard environments.

¡Place the device on a stable surface.

¡The installation site must be free of drafts, dust and caustic fumes.

¡Keep the ventilation slits free and do not obstruct them with other devices.

4.1.1 Spatial requirements

The spatial requirements of the multimeter are: 22.4×10.7×38.7cm . Additional

space is required next to the multimeter to place a PC.

Multimeter and PC can also be placed on separate tables, provided the cable of the mea-

suring tree and/or the USB cable are long enough.

4.1.2 Power supply

WARNING

Danger from electric current

¡Only connect the device to a properly grounded mains outlet.

Before connecting the device to the mains, verify that the operating voltage displayed

on the power module on the back of the multimeter matches the local mains voltage. If

this is not the case, set the correct operating voltage by adjusting the fuse to the local

mains voltage. Please observe the relevant information in the multimeter’s operating

manual for setting the mains voltage

The measuring tree must only be plugged in or unplugged from the multimeter after the

multimeter has been switched off using the power button at the front of the device.

Please observe the relevant information on the electrical connection conditions in the

multimeter manual!

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